Microplate Sealing Solutions

Many different types of microplates rely upon seals to produce accurate, conclusive results.

Cell & Tissue Cultures: Less Contamination, More Gas Exchange

In cell biology, contamination-free products are essential to obtaining accurate results. Active gas exchange (O₂ and CO₂) keeps living cells alive; however, cells also require strict protection against microbial contamination and media evaporation during long incubation periods. 

ELISA Assays: Prevent Evaporation During Incubation

ELISAs are prone to evaporation from the outer-edge wells, also known as the "edge effect." During the multi-hour incubation in which antibodies bind their targets, evaporation may alter the reagent concentrations and testing accuracy.

BCA Assays: Ensuring Uniform Heating

Sealing films play a key role in fluid retention throughout testing and storage. BCAs often require higher-temperature plate incubation to accelerate chemical color reactions. Uneven heat or evaporation caused by poor seals could affect the resulting hues. 

PCR & qPCR Assays: Secure Seals Through Every Cycle

Repeated cycles between extreme temperatures can cause weak adhesive seals to lift or leak, leading to evaporation and/or well-to-well contamination. 

For Light-Sensitive Assays

Cell assays that emit light or use fluorescent dyes that degrade under regular light require stricter sealing and storage. 

—and more!